Research and Discoveries

An experimental chemo-radiation treatment is being tested in newly diagnosed cases of high-risk neuroblastoma – a deadly, hard-to-cure childhood cancer. The experimental radiopharmaceutical, 131I-MIBG, has already shown encouraging results in reducing tumor size in children with relapsed and resistant neuroblastoma. › Continue Reading

Scientists have discovered a new function for a protein that protects cells during injury and could eventually translate into treatment for conditions ranging from cardiovascular disease to Alzheimer’s. Researchers reported yesterday in the journal Cell that a protein called thrombospondin › Continue Reading

There were clues Zeke Angel had eosinophilic esophagitis, an allergic inflammatory condition, long before he could pronounce it. For years, his parents thought he had a sensitive stomach. It wasn’t until he became a teenager and grew sicker that he › Continue Reading

It’s official – in June, you’ll begin to see cranes and earth movers on our main campus as construction on a new 15-story research building gets underway. The new building will be located next door to the research building that › Continue Reading

Even in a world of modern antibiotics, meningitis maintains a stubborn foothold. This bacterial infection of membranes surrounding the brain and spinal cord continues to kill or permanently disable an alarming number of infants, children and adults. Effective vaccination programs › Continue Reading

The news is never short on stories about efforts to make healthcare more effective, more affordable and that endless quest to find new treatments for terrible diseases. Humankind constantly puts together its greatest minds and newest technologies, and then invents even › Continue Reading

Lead never really goes away. The heavy metal doesn’t degrade. So, once a person is exposed and gets lead in their system, it tends to hang around and cause a lot of trouble – sort of like a gift from › Continue Reading

Sports-related concussions continue to be a frequent topic in the media, and new research from Cincinnati Children’s sheds important new light on concussions involving younger athletes. A study recently published by the journal Pediatrics raises questions about how soon student athletes › Continue Reading

Most people know Ryan Dempster as an all-star pitcher who once played for the Cincinnati Reds and now takes the mound for the Chicago Cubs. Dempster’s real heroics, however, are not found in the blazing speed of his fast ball. › Continue Reading

Every year hope is put on hold as promising medical research is delayed while scientists struggle to obtain rare resources vital to their work. The resources are patient tissue and blood samples containing cells, plasma, serum, DNA, RNA and other › Continue Reading

The ongoing debate over what constitutes wasteful government spending spurred a recent dinner conversation among friends over the use of federal tax dollars to study reproductive sciences in small fish and insects. The discussion meandered into someone asking what the › Continue Reading

Cincinnati Children’s scientists have genetically re-engineered a herpes virus to track down early stage cancers and prompt tumor cells to secrete a detectable biomarker that reveals their presence. The research, published in the online journal PLoS (Public Library of Science) › Continue Reading

If you’ve ever wondered exactly how much safer your home would be for small children by using safety devices such as stair gates and cabinet locks, we now have a precise number for you. Seventy percent. About 2,800 U.S. children › Continue Reading

Cincinnati Children’s is leading the way in meeting national goals for delivering the smallest preemies at the places that are best equipped to handle them. A compendium of U.S. Public Health Services/Department of Health and Social Services goals and objectives, › Continue Reading

It made the news in Cincinnati when the state of Ohio’s Third Frontier program awarded a $2 million grant to Cincinnati Children’s to commercially develop new biomedical discoveries from the medical center. Understandably, the grant didn’t generate much coverage outside › Continue Reading

A new breakthrough in stem cell research at Cincinnati Children’s is a critical first step to one day being able to grow new intestinal tissue that can be transplanted into patients with gastrointestinal disease. Published online Dec. 12 by the › Continue Reading

Pregnant moms carry most of the responsibility for an unborn baby’s health. They’re the ones taking prenatal vitamins, drinking more milk, being more careful with their diet. But dads aren’t off the hook, says a Chicago Tribune article referencing a › Continue Reading

Information is power – and the sharing of information among doctors and researchers is one of the best ways to empower physicians to better diagnose and treat ADHD, a chronic condition that affects about 4.5 million children nationwide.  The American › Continue Reading

Imagine if a doctor, treating a young patient with a chronic illness, could have instant access to information from others all around the U.S. on the latest treatments and protocols, how their patients are responding, and what practices are leading › Continue Reading

Comparative effectiveness research is all the rage in medical and political circles these days. It’s the simple-sounding concept of comparing treatments and interventions to figure out which one is best for which patients. It’s not something we’ve done a lot › Continue Reading

The news out of Cincinnati Children’s last week that the age of onset of puberty in girls continues to decline made headlines around the world. A study by Frank Biro, MD, director of Adolescent Medicine, showed that the number of › Continue Reading

Take a moment to imagine a large quantity of something – it can be anything. Got it? Ok, so how much of “something” did you imagine? One hundred? One-hundred thousand? These are both considered large quantities, yet both values pale › Continue Reading

In pediatric medical circles, we take any opportunity to remind anyone who will listen that “children are not small adults.” We make the distinction because treating children takes special care. You can’t just take adult medicine and “cut it down › Continue Reading

We all know computers can do amazing things. But reduce preterm births? No way, right? Well, maybe. One of our neonatologists presented research at the annual meeting of Pediatric Academic Societies earlier this month that explains how. Through computer analysis › Continue Reading

A recap of this week’s news stories (in no particular order) that caught our eye … let us know what you think. Comment below or follow us on Twitter @CincyChildrens for more health news! Oxygen Therapy May Help Preemies Avoid › Continue Reading