Cincinnati Children’s Is One of Nine Avian Flu Testing Sites - Cincinnati Children's Blog

Cincinnati Children’s Is One of Nine Avian Flu Testing Sites

Cincinnati Children’s is one of nine centers nationwide taking part in clinical trials to test the H7N9 avian influenza vaccine in humans. Sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institutes of Health, the purpose of the clinical trials is to determine the safety of the vaccine. In addition, researchers will be studying the immune response it invokes when subjects are given different doses with or without adjuvants, substances designed to boot the body’s immune response to vaccination.

The first human cases of H7N9 influenza occurred in China in February 2013, with the majority of the cases happening in the spring. As of August 12, 135 human cases, including 44 deaths, have been reported by the World Health Organization. Most of those cases involved people who came into contact with infected poultry. Although no H7N9 influenza cases have been reported outside of China, and the virus has not demonstrated sustained person-to-person transmission, there is concern that it could mutate and pose a much greater public health threat.

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