WHAT IS THE BENADRYL CHALLENGE?
The Benadryl challenge is a dangerous social media trend that encourages people, especially teenagers, to take large amounts of diphenhydramine (Benadryl®) to experience hallucinations.
The challenge has been on social media since 2020 but has become popular again. There has been a recent rise in teen overdoses involving diphenhydramine reported by multiple regional poison centers in the U.S.
WHAT IS DIPHENHYDRAMINE?
Diphenhydramine is an antihistamine medication, commonly used to treat seasonal allergies and allergic reactions. Common side effects of this medication include:
- Drowsiness
- Dry mouth
- Difficulty urinating
- Sensations of a racing heart (palpitations)
WHAT ARE THE RISKS OF THE BENADRYL CHALLENGE?
Taking too much diphenhydramine can cause serious health problems, including:
- Slurred speech
- Large pupils
- Increased body temperature
- Irregular heart rhythms
- Seizures
- Death
As the dose increases, the risk for these serious side effects also goes up. Everyone should be aware of the risks and harmful consequences of participating in this challenge.
Teenagers are the most likely group to take part in this challenge. Everyone of all ages should say no to this challenge and others like it.
WHAT ACTION SHOULD PARENTS TAKE RELATED TO THE BENADRYL CHALLENGE?
Talk to your kids about peer pressure
Like any other social media trend, this challenge should be part of a bigger discussion with your kids about the dangers of peer pressure. These posts are often shared to get clicks and views, without warning about the potential dangers involved with these kinds of challenges. Teenagers tend to believe they are invincible and the desire to ‘go viral’ or collect likes/comments can unfortunately get in the way of their better judgement. Monitor their social media accounts and have open communication regarding appropriate use.
Talk to your kids about how to use medications properly
Some teens might think that because a medication is available over-the-counter it is harmless. That’s not the case. Talk to them about the dangers of all medications when they are not used as intended.
Keep medications out of reach
- Store medications in locked cabinets and out of sight and reach of children.
- Keep all medications in original containers with child safety caps.
If A Child Takes Too Much Benadryl
If someone shows serious symptoms, such as seizures or coma, call 911 right away for help. For other symptoms or questions, call the Drug and Poison Information Center (DPIC) at 1-800-222-1222. Specially trained nurses and pharmacists can talk you through what to watch for and advise you on what further action is needed.

