Research and Discoveries

“I’m active.  I feel better.  I’m happy to be alive.”  These are words from Misty Barnhart, a patient of the Tuberous Sclerosis Clinic at Cincinnati Children’s. Before coming to Cincinnati Children’s, Misty had one of her kidneys removed after a procedure › Continue Reading

Imagine taking a fantastic voyage deep into your own eye. As you get smaller and smaller, the world around you becomes surreal. This is the developing retina of a mouse, as seen under a powerful confocal microscope. The green structures › Continue Reading

As dean of the University of Cincinnati medical school – and a physician/researcher who helped make Cincinnati Children’s a top-tier pediatric medical center – Dr. Thomas Boat is not one to exaggerate. So it was noteworthy that, when addressing an › Continue Reading

The stained glass architecture of these insulin-producing cells found deep inside a mouse pancreas brings new meaning to the idea that our bodies are temples.  Researchers at Cincinnati Children’s are studying these cell groups, known as islets of Langerhans, to › Continue Reading

People like Lisa Crawford and her family lived for decades in the shadow of a Cold War nuclear weapons plant – tucked into rolling farmland 18 miles northwest of Cincinnati – unaware they were being exposed to radioactive materials in › Continue Reading

We all know that mothers perform amazing feats every day. But did you know that biologically, the act of becoming a mother actually defies nature? That’s right. The process of successfully carrying a child to term, from a purely immunologic › Continue Reading

Smoking marijuana during pregnancy may be more dangerous than you think, according to the latest research from Cincinnati Children’s. A study led by Sudhansu K. Dey, PhD, director of the Division of Reproductive Science at Cincinnati Children’s, and his colleagues › Continue Reading

This is your brain. Actually, this is your brain’s white matter as seen using a technique called diffusion tensor imaging. White matter and grey matter are the brain’s two main components. White matter, actually pinkish white to the naked eye, › Continue Reading

Scientists have discovered the first direct evidence that a biological mechanism long suspected in epilepsy is capable of triggering brain seizures – opening the door for studies to seek improved treatments or even preventative therapies. Researchers at Cincinnati Children’s Hospital › Continue Reading

Much of what makes us human comes from a part of the brain called the telencephalon, also known as the forebrain. This region controls cognition, emotion and how we move. Inside the forebrain is an area called the amygdala, which › Continue Reading

Hyundai Hope On Wheels® and Cincinnati-area Hyundai dealers awarded Cincinnati Children’s Hospital Medical Center a $75,000 Hyundai Scholar Grant to support the pediatric cancer research of Dr. Maureen O’Brien, who is currently working to identify new therapies that may help › Continue Reading

The following article recently appeared in UC Health News. It has been edited for this format. Cincinnati-based researchers have found that exposure to three types of mold during infancy may have a direct link to asthma development during childhood. These › Continue Reading

Learning from dummies

They sweat. They bleed. They moan. They make great teachers. Patient simulator mannequins play a growing role in training medical students, residents, nurses and other staff at Cincinnati Children’s, especially in critical care. Traditionally, healthcare teaches technical skills, or algorithms › Continue Reading

Today the National Institutes of Health (NIH) announced that James M. Wells, PhD at Cincinnati Children’s Hospital Medical Center is one of 17 investigators nationwide to receive a grant from a $13 million research fund to study the development of › Continue Reading

Members of the Cincinnati Children’s team are currently involved in discovering and developing new treatments for kids with autism spectrum disorders. Learn about the latest research and parent resources. Researchers Report Success in Treating CTD Autism Spectrum Disorder Using a › Continue Reading

While sudden death in teens is rare, it usually occurs during physical activity such as a sporting event. Since November 2011, researchers at Cincinnati Children’s Hospital  have been investigating whether echocardiography should be included as part of screenings to help › Continue Reading

This is the compound eye of Drosophila melanogaster , more commonly known as the fruit fly. Researchers at Cincinnati Children’s use fruit flies as models to learn about the genetic and molecular roots of vision disorders.  Although the structure of › Continue Reading

Erica “Ric” Muskopf says she hopes research will someday change the outcome for patients like her son, Brody. Brody was born with Duchenne muscular dystrophy, a disease that attacks his muscles. Without a cure, it will eventually destroy his heart › Continue Reading

A landmark randomized clinical trial is testing a potentially life prolonging drug treatment to slow down or stop heart damage that usually kills patients diagnosed with Duchenne Muscular Dystrophy (DMD). The study is a collaboration of Cincinnati Children’s Hospital Medical › Continue Reading

Recently we shared with you the story of Jenna Weber, a teenager treated at the Headache Center at Cincinnati Children’s for chronic migraines. Migraine sufferers like Jenna may soon be able to use a new mobile phone app to help › Continue Reading

An experimental chemo-radiation treatment is being tested in newly diagnosed cases of high-risk neuroblastoma – a deadly, hard-to-cure childhood cancer. The experimental radiopharmaceutical, 131I-MIBG, has already shown encouraging results in reducing tumor size in children with relapsed and resistant neuroblastoma. › Continue Reading

Scientists have discovered a new function for a protein that protects cells during injury and could eventually translate into treatment for conditions ranging from cardiovascular disease to Alzheimer’s. Researchers reported yesterday in the journal Cell that a protein called thrombospondin › Continue Reading

There were clues Zeke Angel had eosinophilic esophagitis, an allergic inflammatory condition, long before he could pronounce it. For years, his parents thought he had a sensitive stomach. It wasn’t until he became a teenager and grew sicker that he › Continue Reading

It’s official – in June, you’ll begin to see cranes and earth movers on our main campus as construction on a new 15-story research building gets underway. The new building will be located next door to the research building that › Continue Reading

Even in a world of modern antibiotics, meningitis maintains a stubborn foothold. This bacterial infection of membranes surrounding the brain and spinal cord continues to kill or permanently disable an alarming number of infants, children and adults. Effective vaccination programs › Continue Reading